Pseudo RACK1

Pseudo RACK1, a peptide, is a PKC agonist with homologous sequences of PKC. Pseudo RACK1 interacts selectively with β-PKC at an autoregulatory site (RACK-binding site) and activates it in the absence of PKC activators, following inducing PKC-mediated histone phosphorylation[1].

KKWKMRRNQFWIKIQRC CSVEIWD*

12352209

PKC

Epigenetics; TGF-beta/Smad

Others

O=C(N[C@@H](CCCCN)C(N[C@@H](CC1=CNC2=CC=CC=C12)C(N[C@@H](CCCCN)C(N[C@@H](CCSC)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC(N)=O)C(N[C@@H](CCC(N)=O)C(N[C@@H](CC3=CC=CC=C3)C(N[C@@H](CC4=CNC5=CC=CC=C45)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CCCCN)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CCC(N)=O)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CSSC[C@@H](C(N[C@@H](CO)C(N[C@@H](C(C)C)C(N[C@@H](CCC(O)=O)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CC6=CNC7=CC=CC=C67)C(N[C@@H](CC(O)=O)C(O)=O)=O)=O)=O)=O)=O)=O)N)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CCCCN)N

C144H225N43O34S3

3198.79

[1]Ron D, et al. An autoregulatory region in protein kinase C: the pseudoanchoring site. Proc Natl Acad Sci U S A. 1995 Jan 17;92 (2) :492-6.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-P1371/

Peptides

No Development Reported