PSMA6 Antilichaam

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Multiple transcript variants encoding several different isoforms have been found for this gene. A pseudogene has been identified on the Y chromosome.

5687

P60900

Human, Mouse, Rat, Monkey

Recombinant fusion protein containing a sequence corresponding to amino acids 1-246 of human PSMA6 (NP_002782.1) .

Unconjugated

Primary Antibodies

Cell Cycle

Affinity purification

HepG2

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 27kDa

IgG

PSMA6

HeLa

A-549

COS-7

PC-12

MCF7

Proteasome (prosome, macropain) subunit, alpha type, 6

Homo sapiens

PSMA6, IOTA, MGC22756, MGC2333, MGC23846, PROS27, p27K

WB, IHC, IF

Liquid