PSMA6 Antilichaam - N-terminalgebied: HRP (ARP40419 P050-HRP)

Proteasome (prosome, macropain) subunit, alpha type, 6

IOTA, p27K, PROS27

5687

P60900

NP_002782

Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit, Sheep, Yeast, Zebrafish

The immunogen is a synthetic peptide directed towards the N terminal region of human PSMA6

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. PSMA6 is a member of the peptidase T1A family, which is a 20S core alpha subunit.The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. A pseudogene has been identified on the Y chromosome. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

UBC; RNF170; LIMD2; C19orf57; TRIM39; ZBTB44; CADM1; HUWE1; PSMA3; RTP5; KRTAP4-2; AURKA; PSMD14; MDM2; PSMA5; PSMG3; PSMG2; PSMG1; RNF2; PSMB8; PSMB7; PSMB6; PSMB5; PSMB4; PSMB3; PSMB2; PSMB1; PSMA7; PSMA4; PSMA1; HNRNPA2B1; PYCRL; RPP38; RPP30; CAST; PS

HRP: Horseradish Peroxidase

Polyclonal Antibody

WB

Affinity Purified

PSMA6 is supported by BioGPS gene expression data to be expressed in HeLa

0.5 mg/ml

Cow: 100%; Dog: 100%; Goat: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%; Yeast: 100%; Zebrafish: 100%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

27kDa

Bennett, D.A., (2008) Eur. J. Hum. Genet. 16 (4), 480-486

Wet Ice

246

PSMA6

PSMA6

Rabbit

Proteasome subunit alpha type-6

NM_002791

EYAFKAINQGGLTSVAVRGKDCAVIVTQKKVPDKLLDSSTVTHLFKITEN

Alpha type-6