PSMD11 Antilichaam - C-terminalgebied: FITC (ARP33002 T100-FITC)

Proteasome (prosome, macropain) 26S subunit, non-ATPase, 11

S9, Rpn6, p44.5

5717

O00231

NP_002806

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Yeast, Zebrafish

The immunogen is a synthetic peptide directed towards the C terminal region of human PSMD11

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator.

HUWE1; SUMO2; SUMO3; PSMD14; UBC; MDM2; ASB11; SHFM1; PSMC2; PSMC1; RPS8; PSMD12; PSMD8; PSMD3; PSMD1; PSMC6; PSMC5; KCMF1; PRMT6; UCHL5; KIAA0368; ADRM1; RPS21; RPS15A; PARK2; RNF11; NOS2; SMAD5; SMAD4; SMAD3; SMAD2; SMAD1; FN1; CFTR; VCAM1; LRRK2; env

FITC: Fluorescein Isothiocyanate

Polyclonal Antibody

IHC, WB

0.5 mg/ml

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 100%; Zebrafish: 100%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

47kDa

Conticello, S.G., et al., (2003) Biol. 13 (22), 2009-2013

Wet Ice

422

PSMD11

PSMD11

Rabbit

26S proteasome non-ATPase regulatory subunit 11

NM_002815

ALRYAGRQTEALKCVAQASKNRSLADFEKALTDYRAELRDDPIISTHLAK

11