PTC-209
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
An inhibitor of BMI-1 (IC50 = 500 nM), part of the polycomb repressive complex 1 (PCR1) .1 It inhibited endogenous BMI-1 expression in human colorectal HCT116 and human fibrosarcoma HT1080 tumor cells resulting in reduced tumor volume as well as reduced cancer initiating cell (CIC) number. PTC-209 displayed potent in vivo antitumor effects in several cancer models including breast2, head and neck3, glioblastoma4, prostate5, colon5, and rhabdomyosarcoma6. It also promoted chemically-induced direct cardiac reprogramming of cardiac fibroblasts into cardiac myocytes.7,8
Unconjugated
Yellow solid
-20°C
Beschrijving
PTC-209 Beschikbaar in 5 mg. Bestel eenvoudig online met snelle levering.
Specificaties
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