PTER Antilichaam

PTER Antibody: PTER is a mammalian homolog to bacterial phosphotriesterases, enzymes that hydrolyze phosphotriester-containing organophosphate pesticides. It is expressed primarily in the proximal renal tubules and the gene has been localized in humans to chromosomal band 10p12 by in situ hybridization. PTER, in addition to FTO, MC4R, and NPC1 has recently been shown to be a new risk loci for early-onset and morbid adult obesity in European populations. At least two isoforms of PTER are known to exist.

9317

Q96BW5

CAH73146

Human, Mouse, Rat

Unconjugated

Primary Antibodies

Obesity

PTER Antibody is affinity chromatography purified via peptide column.

Cat. No. 1305 - Human Kidney Tissue Lysate

1 mg/mL

Predicted species reactivity based on immunogen sequence: Bovine: (88%)

PTER Antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

PTER antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IgG

PTER

Phosphotriesterase related

Homo sapiens

Davies JA, Buchman VL, Krylova O, et al. Molecular cloning and expression pattern of rpr-1, a resiniferatoxin-binding, phosphotriesterase-related protein, expressed in rat kidney tubules. FEBS Lett.1997; 410:378-82.

Alimova-Kost MV, Imreh S, Buchman VL, et al. Assignment of phosphotriesterase-related gene (PTER) to human chromosome band 10p12 by in situ hybridization. Cytogenet.. Cell Genet.1998; 83:16-7.

Meyre D, Delplanque J, Chevre JC, et al. Genome-wide associated study for early-onset and morbid adult obesity identifies three new risk loci in European populations. Nat. Genet.2009; 41:157-9.

PTER Antibody: HPHRP, RPR-1, Phosphotriesterase-related protein, Parathion hydrolase-related protein, hPHRP

ELISA, WB, IHC-P

55664514

Liquid