PTHLH Antilichaam

The protein encoded by this gene is a member of the parathyroid hormone family. This hormone, via its receptor, PTHR1, regulates endochondral bone development and epithelial-mesenchymal interactions during the formation of the mammary glands and teeth. It is responsible for most cases of humoral hypercalcemia of malignancy, and mutations in this gene are associated with brachydactyly type E2 (BDE2) . Alternatively spliced transcript variants have been found for this gene. There is also evidence for alternative translation initiation from non-AUG (CUG and GUG) start sites, downstream of the initiator AUG codon, resulting in nuclear forms of this hormone.

5744

P12272

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 25-175 of human PTHLH (NP_945315.1) .

Unconjugated

Primary Antibodies

Cell Cycle, Growth Factors, Signal Transduction

Affinity purification

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

IgG

IHC: 1:50 - 1:200

PTHLH

Parathyroid hormone-like hormone

Homo sapiens

HHM, PLP, BDE2, PTHR, PTHRP, Parathyroid hormone-related protein, Parathyroid hormone-like protein, PTH-rP

IHC

Liquid