PTP4A3 Antilichaam - middengebied: Biotine (ARP51193_P050-Biotine)

Protein tyrosine phosphatase type IVA, member 3

PRL3, PRL-3, PRL-R

11156

O75365

NP_116000

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

The immunogen is a synthetic peptide directed towards the middle region of human PTP4A3

PTP4A3 belongs to a small class of prenylated protein tyrosine phosphatases (PTPs) . PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. This class of PTPs contains a PTP domain and a characteristic C-terminal prenylation motif. Studies of this class of PTPs in mice demonstrated that they were prenylated proteins in vivo, which suggested their association with cell plasma membrane. Overexpression of this gene in mammalian cells was reported to inhibit angiotensin-II induced cell calcium mobilization and promote cell growth.The protein encoded by this gene belongs to a small class of prenylated protein tyrosine phosphatases (PTPs) . PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. This class of PTPs contain a PTP domain and a characteristic C-terminal prenylation motif. Studies of this class of PTPs in mice demonstrated that they were prenylated proteins in vivo, which suggested their association with cell plasma membrane. Overexpression of this gene in mammalian cells was reported to inhibit angiotensin-II induced cell calcium mobilization and promote cell growth. Two alternatively spliced variants exist.

ELAVL1; FNTB; FNTA; IPO4; MMS19; NCAPG; SMAP1; SRPRB; XPO5; TTC27; FANCI; ATAD3A; TMEM33; HEATR1; DNAAF5; TNPO2; CNNM3; KIAA1279; RAB3GAP2; NUP188; KIAA0368; XPO7; GCN1L1; SMC2; LRPPRC; UBE4A; AIFM1; USO1; ABCD3; PSMD3; PRPSAP1; POLD1; HNRNPM; MSH2; MCM3

Biotin

Polyclonal Antibody

WB

Affinity Purified

PTP4A3 is supported by BioGPS gene expression data to be expressed in HEK293T

0.5 mg/ml

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

19kDa

Liang, F., (2008) J. Biol. Chem. 283 (16), 10339-10346

Wet Ice

173

PTP4A3

PTP4A3

Rabbit

Protein tyrosine phosphatase type IVA 3

NM_032611

LGRAPVLVALALIESGMKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQR