PTPN22 Mouse Monoclonal Antibody [Kloon ID: LBI6B1]

This gene encodes of member of the non-receptor class 4 subfamily of the protein-tyrosine phosphatase family. The encoded protein is a lymphoid-specific intracellular phosphatase that associates with the molecular adapter protein CBL and may be involved in regulating CBL function in the T-cell receptor signaling pathway. Mutations in this gene may be associated with a range of autoimmune disorders including Type 1 Diabetes, rheumatoid arthritis, systemic lupus erythematosus and Graves' disease. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Mar 2009]

Carrier-free (BSA/glycerol-free) PTPN22 mouse monoclonal antibody, clone LBI6B1

LYP; LYP1; LYP2; PEP; PTPN8

Homo sapiens protein tyrosine phosphatase non-receptor type 22 (PTPN22), transcript variant 1, mRNA.

26191

Q9Y2R2

Unconjugated

WB 1:2000, IHC 1:1000

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Druggable Genome, Phosphatase

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

PTPN22

https://www.ncbi.nlm.nih.gov/gene/?term=26191

https://www.uniprot.org/uniprot/Q9Y2R2