PTPN6 Antilichaam - middengebied: HRP (ARP61398 P050-HRP)

Protein tyrosine phosphatase, non-receptor type 6

HCP, HCPH, SHP1, SHP-1, HPTP1C, PTP-1C, SHP-1L, SH-PTP1

5777

P29350

NP_002822

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. N-terminal part of this PTP contains two tandem Src homolog (SH2) domains, which act as protein phospho-tyrosine binding domains, and mediate the interaction of this PTP with its substrates. This PTP is expressed primarily in hematopoietic cells, and functions as an important regulator of multiple signaling pathways in hematopoietic cells. This PTP has been shown to interact with, and dephosphorylate a wide spectrum of phospho-proteins involved in hematopoietic cell signaling.

FHL3; UBC; Siglece; PANK4; SAMD4B; SMAD3; TXN; CD300LF; SIGLEC12; LILRB4; LILRB2; TREML1; KIR2DL3; SPATA2; C6orf25; KLRAP1; TMEM62; PILRB; SIGLEC10; FCGR2B; CUZD1; BTLA; SIGLEC11; SLAMF6; TLR10; GAB2; PAG1; PILRA; CLEC4A; KIR2DL5A; ACTN4; BLNK; STAT5B; IR

HRP: Horseradish Peroxidase

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Cow: 93%; Dog: 93%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 93%; Rabbit: 93%; Rat: 93%; Zebrafish: 93%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

65kDa

Wet Ice

595

PTPN6

PTPN6

Rabbit

Tyrosine-protein phosphatase non-receptor type 6

NM_002831

WEEFESLQKQEVKNLHQRLEGQRPENKGKNRYKNILPFDHSRVILQGRDS