PTPRG Antilichaam

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this PTP contains a carbonic anhydrase-like (CAH) domain, which is also found in the extracellular region of PTPRBETA/ZETA. This gene is located in a chromosomal region that is frequently deleted in renal cell carcinoma and lung carcinoma, thus is thought to be a candidate tumor suppressor gene.

5793

P23470

Human, Mouse

Recombinant fusion protein containing a sequence corresponding to amino acids 250-450 of human PTPRG (NP_002832.3) .

Unconjugated

Primary Antibodies

Signal Transduction

Affinity purification

A-549

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 140-162kDa

IgG

WB: 1:500 - 1:2000

PTPRG

293T

Mouse kidney

Mouse heart

Mouse liver

Rat spleen

Protein tyrosine phosphatase, receptor type, G

Homo sapiens

PTPRG, H_RG317H01.1, HPTPG, PTPG, Ptpgamma, RPTPG, PTP gamma, R-PTP-GAMMA

WB

Liquid