PURA Antilichaam - middengebied: Biotine (ARP33202_P050-Biotine)

Purine-rich element binding protein A

PUR1, MRD31, PURALPHA, PUR-ALPHA

5813

Q00577

NP_005850

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit, Sheep

The immunogen is a synthetic peptide directed towards the middle region of human PURA

PURA is a sequence-specific, single-stranded DNA-binding protein. It binds preferentially to the single strand of the purine-rich element termed PUR, which is present at origins of replication and in gene flanking regions in a variety of eukaryotes from yeasts through humans. Thus, it is implicated in the control of both DNA replication and transcription. Deletion of this gene has been associated with myelodysplastic syndrome and acute myelogenous leukemia.This gene product is a sequence-specific, single-stranded DNA-binding protein. It binds preferentially to the single strand of the purine-rich element termed PUR, which is present at origins of replication and in gene flanking regions in a variety of eukaryotes from yeasts through humans. Thus, it is implicated in the control of both DNA replication and transcription. Deletion of this gene has been associated with myelodysplastic syndrome and acute myelogenous leukemia. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

RAF1; UBC; LIN28B; LIN28A; BMI1; TARDBP; IGSF8; ICAM1; IL7R; ZNF638; DDX23; RFC3; RFC2; RB1; PURB; POLA1; CAND1; CUL1; CUL3; EIF2AK2; POU5F1; MEPCE; HNRNPA1; ADAP1; CCNT1; E2F1; SP1; YBX1; CDK5; CNBP; Jvgp5

Biotin

Polyclonal Antibody

IHC, WB

Affinity Purified

PURA is strongly supported by BioGPS gene expression data to be expressed in MCF7

0.5 mg/ml

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

35kDa

Wang, L.G., (2008) Cancer Res. 68 (8), 2678-2688

Wet Ice

322

PURA

PURA

Rabbit

Transcriptional activator protein Pur-alpha

NM_005859

VEFRDYLGDFIEHYAQLGPSQPPDLAQAQDEPRRALKSEFLVRENRKYYM