Puumala Virus Nucleocapsid Antilichaam

Puumala virus (PUUV) is a rodent-borne hantavirus of the family Bunyaviridae, an enveloped, negative-sense RNA viruses with a tripartite genome that can cause hantavirus pulmonary syndrome (HPS) and is highly homologous to the protype hantavirus Hantaan virus (1) . Like other hantaviruses, the PUUV glycoprotein is synthesized as a precursor that is posttranslationally processed into two glycoproteins G1 (Gn) and G2 (Gc) . These glycoproteins interact with the PUUV nucleocapsid (NP) protein through their cytoplasmic tail, and this association has been suggested to be crucial to the binding of the ribonucleoprotein of the PUUV and the assembly of the virus particle (2) .

2943083

P27313

ABO93592

Virus

Unconjugated

Primary Antibodies

Infectious Disease

Puumala virus nucelocapsid antibody is affinity chromatography purified via peptide column.

1 mg/mL

Puumala virus nucleocapsid antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

Puumala virus nucleocapsid antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year.

IgG

Puumala virus nucleocapsid antibody can detect 10ng Puumala virus nucleocapsid peptide in ELISA at 1 μ g/ml.

PUUVsSgp1

PUUVsSgp1

Puumala virus

Vapalahti O, Kallio-Kokko H, Salonen EM, et al. Cloning and sequencing of Puumala virus Sotkamo strain S and M RNA segments: evidence for strain variation in hantaviruses and expression of the nucleocapsid protein. J. Gen. Virol. 1992; 73:829-38.

Hepojoki J, Strandin T, Wang H, et al. Cytoplasmic tails of hantavirus glycoproteins interact with the nucleocapsid protein. J. Gen. Virol. 2010; 91:2341-50.

Puumala Virus Nucleocapsid Antibody: Nucleoprotein, Nucleocapsid protein, Protein N

ELISA

144228123

Liquid