PYGB Antibody - N-terminal regio : FITC (ARP48587 P050-FITC)

Phosphorylase, glycogen; brain

GPBB

5834

P11216

NP_002853

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish

The immunogen is a synthetic peptide directed towards the N terminal region of human PYGB

PYGB is a glycogen phosphorylase found predominantly in the brain. It forms homodimers which can associate into homotetramers, the enzymatically active form of glycogen phosphorylase. The activity of this enzyme is positively regulated by AMP and negatively regulated by ATP, ADP, and glucose-6-phosphate. This enzyme catalyzes the rate-determining step in glycogen degradation. The protein encoded by this gene is a glycogen phosphorylase found predominantly in the brain. The encoded protein forms homodimers which can associate into homotetramers, the enzymatically active form of glycogen phosphorylase. The activity of this enzyme is positively regulated by AMP and negatively regulated by ATP, ADP, and glucose-6-phosphate. This enzyme catalyzes the rate-determining step in glycogen degradation. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

UBC; SIAH1; PYGL; PYGB; SUMO2; SUMO3; WDR61; RIC8A; OGFOD1; UBA6; UBR7; LIMD1; XPNPEP1; PLCG1; FH; NPM1; CPNE1; PSMB2; CAND1; SIRT7; MLH1; ACTN1

FITC: Fluorescein Isothiocyanate

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Cow: 85%; Dog: 92%; Guinea Pig: 86%; Horse: 92%; Human: 100%; Mouse: 100%; Rabbit: 86%; Rat: 92%; Sheep: 85%; Zebrafish: 93%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

97kDa

Lee, M.K., (2006) Pathology 38 (6), 555-560

Wet Ice

843

PYGB

PYGB

Rabbit

Glycogen phosphorylase, brain form

NM_002862

ADDWLRYGNPWEKARPEYMLPVHFYGRVEHTPDGVKWLDTQVVLAMPYDT