Pyridoxamine-5′-fosfaat (standaard)
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Sacubitril (sodium) (Standard) is the analytical standard of Sacubitril (sodium) . This product is intended for research and analytical applications. Sacubitril sodium is a potent and orally active NEP (neprilysin) inhibitor, with an IC50 of 5 nM. Sacubitril sodium enhances the tone of the natriuretic peptide (NP) system and exerts significant antihypertensive effects. Sacubitril sodium is a component of the heart failure medicine LCZ696. Sacubitril sodium can be used for the research of heart failure, hypertension and COVID-19[1][2][3].
529-96-4
12352005
Endogenous Metabolite; Reference Standards
Metabolic Enzyme/Protease; Others
Neurological Disease
O=P(O)(OCC1=CN=C(C)C(O)=C1CN)O
C8H13N2O5P
248.17
[1]Seo JH, et, al. Necessary and sufficient conditions for the asymmetric synthesis of chiral amines using ω-aminotransferases. Biotechnol Bioeng. 2011 Feb;108 (2) :253-63.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-B1746R/
Reference Standards
Beschrijving
Sacubitril (sodium) (Standard) is the analytical standard of Sacubitril (sodium) . This product is intended for research and analytical applications. Sacubitril
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