Pyripyropene B
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Pyripyropene B is a powerful acyl-CoA: cholesterol acyltransferase 2 (ACAT2) inhibitor found in the fungus Aspergillus fumigatus FO 1289. Pyripyropene B inhibits acyl-CoA: cholesterol acyltransferase with an IC50 of 117 nM[1].
151519-44-7
12352005
Acyltransferase
Metabolic Enzyme/Protease
Metabolic Disease
C[C@@]12[C@]3([H])[C@@]([C@H](C[C@@]1([H])[C@@](C)([C@H](CC2)OC(C)=O)COC(CC)=O)OC(C)=O)(OC4=C(C(OC(C5=CN=CC=C5)=C4)=O)[C@@H]3O)C
C32H39NO10
597.65
[1]Y K Kim, et al. Pyripyropenes, novel inhibitors of acyl-CoA:cholesterol acyltransferase produced by Aspergillus fumigatus. II. Structure elucidation of pyripyropenes A, B, C and D. J Antibiot (Tokyo) . 1994 Feb;47 (2) :154-62.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-N14614/
Natural Products
No Development Reported
Beschrijving
Pyripyropene B is a powerful acyl-CoA: cholesterol acyltransferase 2 (ACAT2) inhibitor found in the fungus Aspergillus fumigatus FO 1289. Pyripyropene B inhibit
Specificaties
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