Q14
Gecertificeerd

Q14

Catalog #: TP3624-01
Maat: 10 mg

Kwaliteit

ISO Gecertificeerd

Levering

24-48 uur

Prijs -1%
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Gratis verzending vanaf €100
Technische Documentatie

Technische Specificaties

Target

Mitophagy, DUB

Related Pathways

Ubiquitination, DNA Damage/DNA Repair, Cell Cycle/Checkpoint, Autophagy

Bioactivity

Q14 is a polypeptide derived from the transmembrane (TM) domain of USP30 (ubiquitin specific peptidase30) and is capable of inhibiting the deubiquitination activity of USP30 (IC50=57.2 nM) . By hindering the interaction between USP30’s transmembrane and catalytic domains, it lowers USP30 activity. The Q14 polypeptide contains an LC3 interaction region (LIR) motif, enabling it to bind with LC3, thereby accelerating autophagosome formation and promoting mitophagy. Q14 is applicable in the study of neurodegenerative diseases, mitochondrial quality control, and cellular metabolism.

Molecular Formula

C101H168N32O23

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Beschrijving

Q14 Beschikbaar in 10 mg. Bestel eenvoudig online met snelle levering.

Specificaties

ProductnaamQ14
Categorie
Beschikbare grootte10 mg
CatalogusnummerTP3624-01