QP5

QP5 is an Amelogenin -derived peptide. QP5 binds on the hydroxyapatite and demineralized tooth enamel surfaces, transitorily stabilize the amorphous calcium phosphate (ACP), control the crystallization of hydroxyapatite and promote the remineralization of caries lesions. QP5 promotes remineralization in rat caries models. QP5 can be used for oral diseases like dental caries research[1].

1501983-51-2

12352209

Drug Derivative

Others

Others

O=C(N1[C@@H](CCC1)C(N[C@@H](CC2=CC=C(C=C2)O)C(N[C@@H](CCC(N)=O)C(N3[C@@H](CCC3)C(N[C@@H](C(C)C)C(N[C@@H](CCC(N)=O)C(N4[C@@H](CCC4)C(N[C@@H](CC5=CNC=N5)C(N[C@@H](CCC(N)=O)C(N6[C@@H](CCC6)C(N[C@@H](CCSC)C(N[C@@H](CCC(N)=O)C(N7[C@@H](CCC7)C(N[C@@H](CCC(N)=O)C(N[C@@H]([C@H](O)C)C(N[C@@H](CCCCN)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCC(O)=O)C(N[C@@H](CCC(O)=O)C(N[C@@H](C(C)C)C(N[C@@H](CC(O)=O)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CCC(N)=O)N

C115H178N34O37S

2660.91

[1]Ding L, et al. Remineralization of enamel caries by an amelogenin-derived peptide and fluoride in vitro. Regen Biomater. 2020 Jun;7 (3) :283-292.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-P11111/

Peptides

No Development Reported