Quetiapinesulfoxide (dihydrochloride) (standaard)

Quetiapine sulfoxide (dihydrochloride) (Standard) is the analytical standard of Quetiapine sulfoxide (dihydrochloride) . This product is intended for research and analytical applications. Quetiapine sulfoxide dihydrochloride (Quetiapine S-oxide dihydrochloride) is a main metabolite of Quetiapinem. Quetiapine is a second-generation antipsychotic[1]. Quetiapine is a 5-HT receptors agonist and a dopamine receptor antagonist[2].

329218-11-3

Quetiapine S-oxide dihydrochloride (Standard)

12352005

Drug Metabolite; Reference Standards

Metabolic Enzyme/Protease; Others

Neurological Disease

OCCOCCN(CC1)CCN1C2=NC(C=CC=C3)=C3S(C4=C2C=CC=C4)=O.Cl[H].Cl[H]

C21H27Cl2N3O3S

472.43

[1]Remmerie B, et al. Comparison of Capillary and Venous Drug Concentrations After Administration of a Single Dose of Risperidone, Paliperidone, Quetiapine, Olanzapine, or Aripiprazole. Clin Pharmacol Drug Dev. 2016 Nov;5 (6) :528-537.|[2]Cross AJ, et al. Quetiapine and its metabolite norquetiapine: translation from in vitro pharmacology to in vivo efficacy in rodent models. Br J Pharmacol. 2016 Jan;173 (1) :155-66.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-G0014AR/

Reference Standards