(R) - (+) -Bupivacaine (hydrochloride)

(R) - (+) -Bupivacaine hydrochloride is a voltage-gated sodium channel inhibitor. (R) - (+) -Bupivacaine hydrochloride can selectively block the voltage-gated sodium channels on nerve cell membranes, inhibit the influx of sodium ions, and thus prevent the generation and conduction of nerve impulses, exerting local anesthetic activity. (R) - (+) -Bupivacaine hydrochloride can be used in research of acute pains[1].

27262-46-0

12352005

H302-H315-H319-H335

Sodium Channel

Membrane Transporter/Ion Channel

Neuroscience-Neuromodulation

Neurological Disease

CC(C=CC=C1C)=C1NC([C@@H]2N(CCCC2)CCCC)=O.Cl

C18H29ClN2O

324.89

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

[1]Schmidt AC. The role of molecular structure in the crystal polymorphism of local anesthetic drugs: crystal polymorphism of local anesthetic drugs, part X. Pharm Res. 2005 Dec;22 (12) :2121-33.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-Z6848/

Reference compound2

No Development Reported