(R) -CYP3cide
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
(R) -CYP3cide ((R) -PF-4981517) is the R-isomer of CYP3cide. CYP3cide is a potent, selective and time-dependent inhibitor of cytochrome P4503A4 (CYP3A4).
(R) -PF-4981517
12352005
Cytochrome P450
Metabolic Enzyme/Protease
Others
99.46
CC1=CC=C(C2=C(C3=NN(C)C4=NC=NC(N5C[C@H](N6CCCCC6)CC5)=C43)C=NN2C)C=C1
C26H32N8
456.59
[1]Robert L Walsky, et al. Selective mechanism-based inactivation of CYP3A4 by CYP3cide (PF-04981517) and its utility as an in vitro tool for delineating the relative roles of CYP3A4 versus CYP3A5 in the metabolism of drugs. Drug Metab Dispos. 2012 Sep;40 (9) :1686-97.
Blue Ice
-20°C, 3 years (Powder)
http://file.medchemexpress.com/batch_PDF/HY-18642A/R-CYP3cide-SDS-MedChemExpress.pdf
Reference compound1
No Development Reported
Beschrijving
(R) -CYP3cide ((R) -PF-4981517) is the R-isomer of CYP3cide. CYP3cide is a potent, selective and time-dependent inhibitor of cytochrome P4503A4 (CYP3A4).
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