(R) -Isosakuranetin

(R) -Isosakuranetin is an isomer of Isosakuranetin. Isosakuranetin is a flavanone flavonoid which can be found in the fruit of Citrus bergamia. Isosakuranetin is a TRPM3 blocker[1][2][3].

221362-74-9

12352005

TRP Channel

Membrane Transporter/Ion Channel; Neuronal Signaling

Others

99.56

DMSO : 100 mg/mL (ultrasonic)

OC1=C2C(O[C@H](CC2=O)C3=CC=C(OC)C=C3)=CC(O)=C1

C16H14O5

286.28

[1]Drira R, et al. Isosakuranetin, a 4'-O-methylated flavonoid, stimulates melanogenesis in B16BL6 murine melanoma cells. Life Sci. 2015 Dec 15;143:43-9.|[2]Jia S, et al. Antinociceptive Effects of Isosakuranetin in a Rat Model of Peripheral Neuropathy. Pharmacology. 2017;100 (3-4) :201-207.|[3]Straub I, et al. Flavanones that selectively inhibit TRPM3 attenuate thermal nociception in vivo. Mol Pharmacol. 2013 Nov;84 (5) :736-50.

Room Temperature

-20°C, 3 years; 4°C, 2 years (Powder)

http://file.medchemexpress.com/batch_PDF/HY-N2131A/R-Isosakuranetin-SDS-MedChemExpress.pdf

Natural Products

No Development Reported