(R, S, S) -VH032-PEG5-N3
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
(R, S, S) -VH032-PEG5-N3 is an E3 ligase ligand-linker conjugate comprising a VHL ligand based on VH032 and a 5-unit PEG linker. (R, S, S) -VH032-PEG5-N3 is a click chemistry reagent. It contains an azide group and can undergo copper-catalyzed azido-azynylene cycloaddition (CuAAc) with molecules containing an alkyne group. It can also undergo ring-strain-driven alkyne-azido cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
2766352-74-1
12352005
E3 Ligase Ligand-Linker Conjugates
PROTAC
Cancer
C([C@@H](NC(COCCOCCOCCOCCOCCN=[N+]=[N-])=O)[C@](C)(C)C)(=O)N1[C@@H](C(NCC2=CC=C(C=C2)C3=C(C)N=CS3)=O)C[C@H](O)C1
C34H51N7O9S
733.88
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-W999557/
Reference compound1
No Development Reported
Von Hippel-Lindau (VHL)
Beschrijving
(R, S, S) -VH032-PEG5-N3 is an E3 ligase ligand-linker conjugate comprising a VHL ligand based on VH032 and a 5-unit PEG linker. (R, S, S) -VH032-PEG5-N3 is a c
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