R428
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
R428 (1037624-75-1) is a potent and selective inhibitor of AXL kinase (IC50 = 1.4nM) .1 R428 has been shown to overcome chemotherapy resistance to various agents in multiple cancer models.2-5 AXL has been shown to suppress myeloid cell activation and function – combined AXL inhibition with R428 and PD-1 blockade showed potent synergistic antitumor effects.6,7
Unconjugated
Yellow solid
-20°C
Beschrijving
R428 Beschikbaar in 5 mg. Bestel eenvoudig online met snelle levering.
Specificaties
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