RAB3IP Antilichaam / Rab3A-interactief eiwit

RAB3A-interacting protein is a protein that in humans is encoded by the RAB3IP gene. RAB3IP, also hnown as Rabin8, is a deduced 476-amino acid protein containing a central coiled-coil domain, a bipartite nuclear localization signal, and a C-terminal endoplasmic reticulum retention motif. Rabin8 has several sites for N-glycosylation and phosphorylation. Rabin8 plays important roles in various cellular processes, including ciliogenesis.The GEF activity of Rabin8 towards Rab8 is essential for ciliogenesis and cyst apical membrane transport, but not for exocytosis of discoidal/fusiform-shaped vesicles.

Western blot: 0.5-1 µg/mL, Immunohistochemistry (FFPE) : 2-5 µg/mL, Flow cytometry: 1-3ug/million cells, ELISA: 0.1-0.5 µg/mL

Q96QF0

Human, Mouse, Rat

An E.coli-derived human recombinant protein (amino acids F25-R426) was used as the immunogen for the RAB3IP antibody.

WB, IHC-P, FACS, ELISA

Antigen affinity purified

Antigen affinity purified

Lyophilized from 1X PBS with 2% Trehalose

This RAB3IP antibody is available for research use only.

After reconstitution, the RAB3IP antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Optimal dilution of the RAB3IP antibody should be determined by the researcher.

Cytoplasm, Nucleus

IHC staining of FFPE human liver cancer tissue with RAB3IP antibody. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.