Rabusertib (LY260368)
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
911222-45-2
IC-83
C08731-5mg
Chk
Cell Cycle
CC1=CC (=C (C=C1Br) NC (=O) NC2=NC=C (N=C2) C) OCC3CNCCO3
C18H22BrN5O3
Rabusertib (LY2603618, IC-83) is a highly selective Chk1 inhibitor with potential anti-tumor activity in a cell-free assay. IC50=7 nM, showing approximately 100-fold more potent against Chk1 than against any of the other protein kinases evaluated. Rabusertib (LY2603618) induces cell cycle arrest, DNA damage response and autophagy in cancer cells. Rabusertib (LY2603618) induces bak-dependent apoptosis in AML cell lines.
2 years -80 in solvent
Beschrijving
Rabusertib (LY260368) Beschikbaar in 5 mg. Wordt geleverd met droogijs. Bestel eenvoudig online met snelle levering.
Specificaties
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