(Rac) -BX 048
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
(Rac) -BX 048 is a BX 048 racemate. BX 048 is a P2Y12 receptor antagonist. BX 048 inhibits ADP-induced platelet aggregation in human, dog and rat whole blood. BX 048 also inhibits Arachidonic acid induced platelet aggregation (IC50 of 15 μM).
478005-11-7
12352005
H302-H315-H319-H335
P2Y Receptor
GPCR/G Protein
Cardiovascular Disease
O=C(O)CCC(NC(C1=NC2=CC(C)=CC=C2C(OC(C)(C)C(O)=O)=C1)=O)C(N3CCN(C(OCC)=O)CC3)=O
C27H34N4O9
558.58
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
[1]Post JM, et al. Novel P2Y12 adenosine diphosphate receptor antagonists for inhibition of platelet aggregation (II) : pharmacodynamic and pharmacokinetic characterization. Thromb Res. 2008;122 (4) :533-40.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-W419570/
Reference compound1
No Development Reported
P2Y12 Receptor
Beschrijving
(Rac) -BX 048 is a BX 048 racemate. BX 048 is a P2Y12 receptor antagonist. BX 048 inhibits ADP-induced platelet aggregation in human, dog and rat whole blood. B
Specificaties
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