Ractopamine-d5 (hydrochloride)

Ractopamine-d5 (LY031537-d5) hydrochloride is the deuterium labeled Ractopamine hydrochloride. Ractopamine (LY031537) hydrochloride is a potent β-adrenergic receptor (βAR) agonist with Kd values of ~25 nM for pig β1AR and β2AR. Ractopamine hydrochloride is linked to protein metabolism. Ractopamine hydrochloride can be used for researching to increase lean tissue growth and improve production efficiency in pigs[1][2][3].

3072709-33-9

LY031537-d5

12352005

Adrenergic Receptor; Isotope-Labeled Compounds

GPCR/G Protein; Neuronal Signaling; Others

Metabolic Disease

10 mM in DMSO

OC(CNC(C)CCC1=C([2H])C([2H])=C(O)C([2H])=C1[2H])([2H])C2=CC=C(O)C=C2.Cl

C18H19D5ClNO3

342.87

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Athayde NB, et al. Stress susceptibility in pigs supplemented with ractopamine. J Anim Sci. 2013;91 (9) :4180-4187.|[3]Anderson PT, et al. Ractopamine increases total and myofibrillar protein synthesis in cultured rat myotubes. J Nutr. 1990;120 (12) :1677-1683. |[4] S. E. Mills, Biological basis of the ractopamine response, Journal of Animal Science, Volume 80, Issue E-suppl_2, 2002, Pages E28-E32.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-B1421S3/

Isotope-Labeled Compounds

No Development Reported