RAD18 Antilichaam

The protein encoded by this gene is highly similar to S. cerevisiae DNA damage repair protein Rad18. Yeast Rad18 functions through its interaction with Rad6, which is an ubiquitin-conjugating enzyme required for post-replication repair of damaged DNA. Similar to its yeast counterpart, this protein is able to interact with the human homolog of yeast Rad6 protein through a conserved ring-finger motif. Mutation of this motif results in defective replication of UV-damaged DNA and hypersensitivity to multiple mutagens.

56852

Q9NS91

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 216-495 of human RAD18 (NP_064550.3) .

Unconjugated

Primary Antibodies

Cell Cycle

Affinity purification

K-562

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 80kDa

IgG

RAD18

MCF7

Jurkat

293T

Mouse liver

RAD18 homolog (S. cerevisiae)

Homo sapiens

RAD18, RNF73

WB, IHC, IF

Liquid