RAD21 (356

RAD21 (356–395) TFA is a peptide encompassing amino acids 356 to 395 of the RAD21 protein, which can be used to study the interaction mechanism between STAG1 and RAD21. The equilibrium dissociation constant (KD) value for the interaction between RAD21 (356–395) TFA and STAG1 is 127 nM[1].

12352209

Others

Others

Cancer-programmed cell death

Cancer

O=C([C@H]1NCCC1)N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N2[C@H](C(N[C@H](C(N[C@H](C(N3[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N4[C@H](C(O)=O)CCC4)=O)[C@@H](C)O)=O)CC(C)C)=O)CS)=O)CCCNC(N)=N)=O)[C@@H](C)O)=O)CC5=CC=CC=C5)=O)CC(C)C)=O)CCCCN)=O)CC(C)C)=O)CC(C)C)=O)CCCNC(N)=N)=O)CC(N)=O)=O)CC(N)=O)=O)CC6=CNC7=CC=CC=C67)=O)CC(C)C)=O)CCC3)=O)CCC(N)=O)=O)C)=O)CCC2)=O)CC(C)C)=O)CO)=O)CC8=CC=CC=C8)=O)CC(C)C)=O)CCCCN)=O)CCC(O)=O)=O)C(C)C)=O)=O)=O)[C@@H](C)O)=O)CCC(O)=O)=O)CCCCN)=O)CC9=CNC%10=CC=CC=C9%10)=O)CCSC)=O)CCSC)=O)CC(C)C)=O)CCCCN)=O)CCCCN)=O)[C@@H](C)O.OC(C(F)(F)F)=O.[x]

C217H350N56O53S3.xC2HF3O2

4687.64 (free base)

[1]van der Lelij P, et al. STAG1 vulnerabilities for exploiting cohesin synthetic lethality in STAG2-deficient cancers. Life Sci Alliance. 2020 May 28;3 (7) :e202000725.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-P10931A/

Peptides

No Development Reported