RAD23A Antibody - N-terminal regio : HRP (ARP42210_T100-HRP)

RAD23 homolog A (S. cerevisiae)

HR23A, HHR23A

5886

P54725

NP_005044

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

The immunogen is a synthetic peptide directed towards the N terminal region of human RAD23A

RAD23A is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in nucleotide excision repair (NER) . This protein was shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, as well as with ubiquitin protein ligase E6AP, and thus suggests that this protein may be involved in the ubiquitin mediated proteolytic pathway in cells.The protein encoded by this gene is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in nucleotide excision repair (NER) . This protein was shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, as well as with ubiquitin protein ligase E6AP, and thus suggests that this protein may be involved in the ubiquitin mediated proteolytic pathway in cells.

USP25; ZBTB44; TRIP6; TRAF5; TRAF2; ZBTB8A; ANKRD40; FAM188A; TRIM54; NGLY1; CEP250; CEP76; UBC; SHFM1; vpr; XPC; DCTPP1; OGFOD1; UBA6; UBE2R2; TRNT1; HERC4; NT5C2; FKBP9; PCNA; HEXA; CDC34; GNPDA1; GTF3C4; USP5; WARS; TBCE; PYGL; PARP1; SH3RF2; PARK2; SQ

HRP: Horseradish Peroxidase

Polyclonal Antibody

IHC, WB

RAD23A is supported by BioGPS gene expression data to be expressed in Jurkat

0.5 mg/ml

Cow: 93%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

40kDa

Ju, D. (2006) Biochem. Biophys. Res. Commun. 341 (2), 648-652

Wet Ice

363

RAD23A

RAD23A

Rabbit

UV excision repair protein RAD23 homolog A

NM_005053

VPSSGSSGREEDAASTLVTGSEYETMLTEIMSMGYERERVVAALRASYNN