Raf1 (fosfo Ser338) Antilichaam

Involved in the transduction of mitogenic signals from the cell membrane to the nucleus. Part of the Ras-dependent signaling pathway from receptors to the nucleus. Protects cells from apoptosis mediated by STK3.

5894

P04049

NP_002871.1

Human, Mouse

Raf1 (Phospho-Ser338) antibody was raised against a peptide sequence around phosphorylation site of serine 338 (R-D-S (p) -S-Y) derived from Human RAF.

Unconjugated

Primary Antibodies

Phospho-Specific, Apoptosis, Cancer

Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

1 mg/mL

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Phospho-Specific

Blue Ice

Store antibody at -20˚ C for up to one year.

73 kDa

This antibody detects endogenous level of Raf1 only when phosphorylated at serine 338.

Western Blot: 1:500~1:1000

RAF1

V-raf-1 murine leukemia viral oncogene homolog 1

Homo sapiens

Adams DG, et al. (2005) J Biol Chem. 280 (52) : 42644-54. Miura S, et al. (2003) Biochem Biophys Res Commun. 306 (4) : 924-9. Noser JA, et al. (2007) Mol Ther. 15 (8) : 1531-6.

NS5, CRAF, Raf-1, c-Raf, JAK1A, JAK1B, C-RAF, C-Raf

WB

4506401

Liquid