RAF709
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
1628838-42-5
C13593-5mg
Raf
MAPK
CC1=C (C=C (C=N1) NC (=O) C2=CC (=CC=C2) C (F) (F) F) C3=CC (=C (N=C3) OC4CCOCC4) N5CCOCC5
C28H29F3N4O4
RAF709 is a potent inhibitor of B/C RAF kinase with almost equivalent IC50 values of 0.4 nM for B-RAF and C-RAF, showing a high level of selectivity, demonstrating greater than 99% on-target binding to BRAF, BRAFV600E, and CRAF at 1 μM and very few off-targets with DDR1 (>99%), DDR2 (86%), FRK (92%), and PDGFRb (96%), the only kinases with binding >80% at 1 μM.
2 years -80 in solvent
Beschrijving
RAF709 Beschikbaar in 5 mg. Wordt geleverd met droogijs. Bestel eenvoudig online met snelle levering.
Specificaties
Recent bekeken producten
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NP (4-hydroxy-3-nitrophenylacetate)
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ExactaCruz® Pipette Tip Reload System, 50-1250 μl, case
sc-201714
80 Racks/Case
Disc Membrane Hydrophobic PTFE, 0.22μm
CPTB14222
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Rat Serum Albumin
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Denhardt's Solution (50X)
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FKBP4, ID (FK506-binding Protein 4, Peptidyl-prolyl cis-trans Isomerase FKBP4, PPIase FKBP4, Rotamase, HSP-binding Immunophilin, HBI, FKBP52 Protein, 52kD FK506-binding Protein, 52kD FKBP, FKBP-52, 59kD Immunophilin, FKBP59, p59 Protein, FKBP-4, FKBP52)
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West Nile Virus, NS3 Protease (WNV)
MBS603723-01
0.1 mg
Recent gezochte producten
BSA and BGG Stock standards (1 vial each @ 2 mg/ml) for BCA Optima Protein Assay kit
BSA-BGG-1
1 PK
General Bovine Serum Albumin (BSA) ELISA Kit
DL-BSA-Ge-01
48 Tests
General Bovine Serum Albumin (BSA) ELISA Kit
RD-BSA-Ge-01
96 Tests
Heparin
BSA-Hep-01 – 10 mg
10 mg
NP (4-hydroxy-3-nitrophenylacetate)
NP-BSA-03High – 10 mg
10 mg
NP (4-hydroxy-3-nitrophenylacetate)
NP-BSA-03High – 50 mg
50 mg
NP (4-hydroxy-3-nitrophenylacetate)
NP-BSA-03Low – 10 mg
10 mg
NP (4-hydroxy-3-nitrophenylacetate)
NP-BSA-03Low – 50 mg
50 mg