RANBP1 Antilichaam - C-terminalgebied: FITC (ARP46083_P050-FITC)

RAN binding protein 1

HTF9A

5902

P43487

NP_002873

Human, Cow, Horse, Yeast

The immunogen is a synthetic peptide directed towards the C terminal region of human RANBP1

Ran/TC4-binding protein, RanBP1, interacts specifically with GTP-charged RAN. RANBP1 encodes a 23-kD protein that binds to RAN complexed with GTP but not GDP. RANBP1 does not activate GTPase activity of RAN but does markedly increase GTP hydrolysis by the RanGTPase-activating protein (RanGAP1) . The RANBP1 cDNA encodes a 201-amino acid protein that is 92% similar to its mouse homolog. In both mammalian cells and in yeast, RANBP1 acts as a negative regulator of RCC1 by inhibiting RCC1-stimulated guanine nucleotide release from RAN.Ran/TC4-binding protein, RanBP1, interacts specifically with GTP-charged RAN. RANBP1 encodes a 23-kD protein that binds to RAN complexed with GTP but not GDP. RANBP1 does not activate GTPase activity of RAN but does markedly increase GTP hydrolysis by the RanGTPase-activating protein (RanGAP1) . The RANBP1 cDNA encodes a 201-amino acid protein that is 92% similar to its mouse homolog. In both mammalian cells and in yeast, RANBP1 acts as a negative regulator of RCC1 by inhibiting RCC1-stimulated guanine nucleotide release from RAN. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

UBC; SUMO1; MDM2; CHMP4A; PLS3; IDH1; DCK; EGFR; PTMA; RAN; rna1; XPO1; vpu; VCAM1; FN1; CFTR; HNF1A; KPNB1; RCC1; C18orf8; UBD; ELAVL1; Ranbp2; RANGRF; CD93; MPG

FITC: Fluorescein Isothiocyanate

Polyclonal Antibody

WB

Affinity Purified

RANBP1 is strongly supported by BioGPS gene expression data to be expressed in 721_B

0.5 mg/ml

Cow: 79%; Horse: 79%; Human: 100%; Yeast: 90%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

23kDa

Tedeschi, A., J. Cell. Sci. 120 (PT 21), 3748-3761 (2007)

Wet Ice

201

RANBP1

RANBP1

Rabbit

Ran-specific GTPase-activating protein

NM_002882

KFEECRKEIEEREKKAGSGKNDHAEKVAEKLEALSVKEETKEDAEEKQ