RANTES Antilichaam

RANTES is a chemoattractant for blood monocytes, memory T helper cells and eosinophils. It causes the release of histamine from basophils and activates eosinophils. It binds to CCR1, CCR3, CCR4 and CCR5 and is one of the major HIV suppressive factors produced by CD8+ T cells. Recombinant RANTES protein induces a dose dependent inhibition of different strains of HIV 1, HIV 2, and simian immunodeficiency virus (SIV) . It is T cell and macrophage specific, induced by mitogens, and belongs to the intercrine beta (chemokine CC) family.

20304

P30882

P30882

Mouse

Produced from sera of rabbits pre-immunized with highly pure (>98%) recombinant mRANTES (murine RANTES) .

Unconjugated

Primary Antibodies, Functional Antibodies, Antibody Pairs

Chemokines & Cytokines

Anti-mRANTES specific antibody was purified by affinity chromatography employing immobilized mRANTES matrix.

Batch dependent

None

Room Temp

RANTES antibody is stable for at least 2 years from date of receipt at -20˚ C. The reconstituted antibody is stable for at least two weeks at 2-8˚ C. Frozen aliquots are stable for at least 6 months when stored at -20˚ C. Avoid repeated freeze-thaw cycles.

Ccl5

Chemokine (C-C motif) ligand 5

Mus musculus

SISd, Scya5, RANTES, TCP228, MuRantes, C-C motif chemokine 5

ELISA, WB, Neutralization Assay

548926

Lyophilized