RANTES Antilichaam [5B3-D5]

RANTES is a chemoattractant for blood monocytes, memory T helper cells and eosinophils. It causes the release of histamine from basophils and activates eosinophils. It binds to CCR1, CCR3, CCR4 and CCR5 and is one of the major HIV suppressive factors produced by CD8+ T cells. Recombinant RANTES protein induces a dose dependent inhibition of different strains of HIV 1, HIV 2, and simian immunodeficiency virus (SIV) . It is T cell and macrophage specific, induced by mitogens, and belongs to the intercrine beta (chemokine CC) family.

6352

P13501

P13501

Human

Monoclonal antibody against human RANTES designated as VL-1 was purified from ascites fluid on a Protein A affinity column.

5B3-D5

Unconjugated

Primary Antibodies, Functional Antibodies

Chemokines & Cytokines

Batch dependent

None

Room Temp

RANTES lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20˚ C. Reconstitute in sterile water to a concentration of 0.1 - 1.0 mg/mL. The antibody is stable for at least six weeks at 2-4˚ C when reconstituted.

RANTES antibody was derived form BALB/c mice and belongs to the IgG2b isotype.

CCL5

Chemokine (C-C motif) ligand 5

Homo sapiens

Regulated upon activation normally T expressed and presumably secreted, CCL5, TCP228, SISd, D17S136E, SCYA5, C-C motif chemokine 5, EoCP, eoCP, RANTES, SIS-delta

ELISA, WB, Neutralization Assay

6175077

Lyophilized