RAP-103
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
RAP-103 is an orally active CCR antagonist that provides potent synaptic protection by inhibiting and reversing cytoskeletal changes induced by PrPC/NOX signaling. RAP-103 is potentially useful in Alzheimer's disease (AD) research[1].
1337998-99-8
12352209
CCR
GPCR/G Protein; Immunology/Inflammation
Neuroscience-Neurodegeneration
Neurological Disease
C[C@H](O)[C@H](C(O)=O)NC([C@@H](CC1=CC=C(O)C=C1)NC([C@@H](CC(N)=O)NC([C@@H]([C@@H](O)C)NC([C@@H]([C@@H](O)C)N)=O)=O)=O)=O
C25H38N6O11
598.60
[1]Kuhn TB, et al. Chemokine Receptor Antagonists Prevent and Reverse Cofilin-Actin Rod Pathology and Protect Synapses in Cultured Rodent and Human iPSC-Derived Neurons. Biomedicines. 2024 Jan 1;12 (1) :93.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-P11319/
Peptides
No Development Reported
Beschrijving
RAP-103 is an orally active CCR antagonist that provides potent synaptic protection by inhibiting and reversing cytoskeletal changes induced by PrPC/NOX signali
Specificaties
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Modular Incubator Chamber
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SsDNA Assay Kit
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Recent gezochte producten
Biotin-Recombinant (sf9) Marburg virus glycoprotein (Musoke, HA-tag, >95%), purified
MVGP16-BTN
100 µL
MARV VP40/Marburg VP40 Protein (N-His, Lake Victoria marburgvirus (strain Musoke-80) (MARV) (Marburg virus (strain Kenya/Musoke/1980) ) )
P505862
100 µg
X4RF Refrigerated Centrifuge
75009936
1 Each
Low Speed Refrigerated Centrifuge
LX104LSR
1 Unit
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Low Speed Refrigerated Centrifuge
LX124LSR
1 Unit
Blood Bank Refrigerator
LX4000BBR
1 Unit
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LX4002BBR
1 Unit