RAPGEF1 Antilichaam

This gene encodes a human guanine nucleotide exchange factor. It transduces signals from CRK by binding the SH3 domain of CRK, and activating several members of the Ras family of GTPases. This signaling cascade that may be involved in apoptosis, integrin-mediated signal transduction, and cell transformation. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some variants has not been determined.

2889

Q13905

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 844-1095 of human RAPGEF1 (NP_941372.1) .

Unconjugated

Primary Antibodies

Cell Cycle, Signal Transduction

Affinity purification

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

IgG

RAPGEF1

Rap guanine nucleotide exchange factor 1

Homo sapiens

C3G, GRF2, rap guanine nucleotide exchange factor 1, CRK SH3-binding GNRP, Rap guanine nucleotide exchange factor (GEF) 1, guanine nucleotide-releasing factor 2 (specific for crk proto-oncogene)

WB, IHC, IF

Liquid