RAPGEF1 Antilichaam - C-terminalgebied: Biotine (ARP54753 P050-Biotin)

Rap guanine nucleotide exchange factor (GEF) 1

C3G, GRF2

2889

Q13905

NP_005303

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Zebrafish

The immunogen is a synthetic peptide directed towards the C terminal region of human RAPGEF1

RAPGEF1 is a human guanine nucleotide exchange factor. It transduces signals from CRK by binding the SH3 domain of CRK, and activating several members of the Ras family of GTPases. This signaling cascade protein may be involved in apoptosis, integrin-mediated signal transduction, and cell transformation.This gene encodes a human guanine nucleotide exchange factor. It transduces signals from CRK by binding the SH3 domain of CRK, and activating several members of the Ras family of GTPases. This signaling cascade that may be involved in apoptosis, integrin-mediated signal transduction, and cell transformation. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some variants has not been determined.

UBC; MBIP; SLC20A1; ATXN1; RPS15; CRKL; CRK; CBL; GRB2; NEDD9; RHOQ; BCAR1; SHC1; RRAS2; HRAS; RAP1B; HCK; RAP1A

Biotin

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rat: 100%; Zebrafish: 100%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

120kDa

Niclas, J., (2007) Exp. Cell Res. 313 (18), 3881-3891

Wet Ice

1077

RAPGEF1

RAPGEF1

Rabbit

Rap guanine nucleotide exchange factor 1

NM_005312

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