RARB Antilichaam

This gene encodes retinoic acid receptor beta, a member of the thyroid-steroid hormone receptor superfamily of nuclear transcriptional regulators. This receptor localizes to the cytoplasm and to subnuclear compartments. It binds retinoic acid, the biologically active form of vitamin A which mediates cellular signalling in embryonic morphogenesis, cell growth and differentiation. It is thought that this protein limits growth of many cell types by regulating gene expression. The gene was first identified in a hepatocellular carcinoma where it flanks a hepatitis B virus integration site. Alternate promoter usage and differential splicing result in multiple transcript variants.

5915

P10826

Human, Mouse, Rat

A synthetic peptide of human RARB

Unconjugated

Primary Antibodies

Cancer, Cell Cycle, Signal Transduction, Transcription

Affinity purification

A-549

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 60kDa

IgG

RARB

BT-474

NCI-H460

Retinoic acid receptor, beta

Homo sapiens

RARB, HAP, NR1B2, RRB2, MCOPS12

WB, IHC, IF

Liquid