RAS-IN-5
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
RAS-IN-5 (Example 2) is a RAS inhibitor. RAS-IN-5 significantly inhibits the interaction between RAF1 and active KRAS mutant protein or HRAS WT protein. RAS-IN-5 significantly inhibits the cell viability of KRAS, NRAS, and EGFR mutant cells. RAS-IN-5 can be used in the research of colorectal cancer, liver cancer, and non-small cell lung cancer[1].
3061844-70-7
12352005
Ras
GPCR/G Protein; MAPK/ERK Pathway
Cancer-Kinase/protease
Cancer
CCN1C2=C3C=C(C4=CC(C[C@@H](C(N5CCC[C@@H](C(OCC(C)(CC3=C1C6=C(C=CC(P(C)(C)=O)=C6)[C@@H](OC)C)C)=O)N5)=O)NC([C@@H](N(C([C@@H]7OCC[C@@H]7C8=CC=CC=C8)=O)C)C(C)C)=O)=CC(O)=C4)C=C2
C57H72N5O9P
1002.18
[1]TONG, et al. Macrocyclic compounds and therapeutic uses thereof. WO2024222864A1. WIPO (PCT) . 2024-04-26.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-W1126467/
Reference compound1
No Development Reported
Beschrijving
RAS-IN-5 (Example 2) is a RAS inhibitor. RAS-IN-5 significantly inhibits the interaction between RAF1 and active KRAS mutant protein or HRAS WT protein. RAS-IN-
Specificaties
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