RASGRP3 Mouse Monoclonal Antibody [Kloon ID: LBI3B9]

Members of the RAS (see HRAS; MIM 190020) subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RASGRP3, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation (Rebhun et al., 2000 [PubMed 10934204]) . [supplied by OMIM, Mar 2008]

Carrier-free (BSA/glycerol-free) RASGRP3 mouse monoclonal antibody, clone LBI3B9

GRP3

Homo sapiens RAS guanyl releasing protein 3 (RASGRP3), transcript variant 2, mRNA.

25780

Q8IV61

Unconjugated

B cell receptor signaling pathway, MAPK signaling pathway

B cell receptor signaling pathway, MAPK signaling pathway

WB 1:2000

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

RASGRP3

https://www.ncbi.nlm.nih.gov/gene/?term=25780

https://www.uniprot.org/uniprot/Q8IV61