RBBP4 Antilichaam

This gene encodes a ubiquitously expressed nuclear protein which belongs to a highly conserved subfamily of WD-repeat proteins. It is present in protein complexes involved in histone acetylation and chromatin assembly. It is part of the Mi-2 complex which has been implicated in chromatin remodeling and transcriptional repression associated with histone deacetylation. This encoded protein is also part of co-repressor complexes, which is an integral component of transcriptional silencing. It is found among several cellular proteins that bind directly to retinoblastoma protein to regulate cell proliferation. This protein also seems to be involved in transcriptional repression of E2F-responsive genes. Three transcript variants encoding different isoforms have been found for this gene.

5928

Q09028

Human

Recombinant fusion protein containing a sequence corresponding to amino acids 1-425 of human RBBP4 (NP_005601.1) .

Unconjugated

Primary Antibodies

Cancer, Cell Cycle

Affinity purification

SW480

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 48kDa

IgG

RBBP4

HeLa

Jurkat

293T

Retinoblastoma binding protein 4

Homo sapiens

RBAP48, Histone-binding protein RBBP4, Chromatin assembly factor 1 subunit C, CAF-1 subunit C, NURF55

WB, IF, ChIP

Liquid