RBBP6 Polyklonale Antilichaam, HRP-vervoeging

E3 ubiquitin-protein ligase which promotes ubiquitination of YBX1, leading to its degradation by the proteasome. May play a role as a scaffold protein to promote the assembly of the p53/TP53-MDM2 complex, resulting in increase of MDM2-mediated ubiquitination and degradation of p53/TP53; may function as negative regulator of p53/TP53, leading to both apoptosis and cell growth.

PACT; MY038; P2P-R; RBQ-1; SNAMA; E3 ubiquitin-protein ligase RBBP6; Proliferation potential-related protein; Protein P2P-R; Retinoblastoma-binding Q protein 1; Retinoblastoma-binding protein 6; p53-associated cellular protein of testis; RBBP6; P2PR; RBQ1

5930

Q7Z6E9

Cytoplasm, Nucleus

Mouse

2-150/1792

RBBP6

HRP

KLH conjugated synthetic peptide derived from human P2PR

WB, ELISA, IHC-P, IHC-F

Purified by Protein A.

1µg/µl

WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500)

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Unmodified

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

5930

Human, Rat