RBM8A Antilichaam

This gene encodes a protein with a conserved RNA-binding motif. The protein is found predominantly in the nucleus, although it is also present in the cytoplasm. It is preferentially associated with mRNAs produced by splicing, including both nuclear mRNAs and newly exported cytoplasmic mRNAs. It is thought that the protein remains associated with spliced mRNAs as a tag to indicate where introns had been present, thus coupling pre- and post-mRNA splicing events. Previously, it was thought that two genes encode this protein, RBM8A and RBM8B; it is now thought that the RBM8B locus is a pseudogene. There are two alternate translation start codons with this gene, which result in two forms of the protein. An allele mutation and a low-frequency noncoding single-nucleotide polymorphism (SNP) in this gene cause thrombocytopenia-absent radius (TAR) syndrome.

9939

Q9Y5S9

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 1-80 of human RBM8A (NP_005096.1) .

Unconjugated

Primary Antibodies

Other

Affinity purification

U251

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 20kDa

IgG

WB: 1:500 - 1:2000

RBM8A

HT-29

HepG2

HeLa

293T

Mouse brain

RNA binding motif protein 8A

Homo sapiens

RBM8A, TAR, Y14, RBM8, ZNRP, RBM8B, ZRNP1, BOV-1A, BOV-1B, BOV-1C, MDS014, DEL1q21.1, C1DELq21.1

WB

Liquid