RBM8A Antilichaam - N-terminalgebied: FITC (ARP40576_T100-FITC)

RNA binding motif protein 8A

TAR, Y14, RBM8, ZNRP, RBM8B, ZRNP1, BOV-1A, BOV-1B, BOV-1C, MDS014, DEL1q21.1, C1DELq21.1

9939

Q9Y5S9

NP_005096

Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit, Zebrafish

The immunogen is a synthetic peptide directed towards the N terminal region of human RBM8A

RBM8A is a protein with a conserved RNA-binding motif. The protein is found predominantly in the nucleus, although it is also present in the cytoplasm. It is preferentially associated with mRNAs produced by splicing, including both nuclear mRNAs and newly exported cytoplasmic mRNAs. It is thought that the protein remains associated with spliced mRNAs as a tag to indicate where introns had been present, thus coupling pre- and post-mRNA splicing events.This gene encodes a protein with a conserved RNA-binding motif. The protein is found predominantly in the nucleus, although it is also present in the cytoplasm. It is preferentially associated with mRNAs produced by splicing, including both nuclear mRNAs and newly exported cytoplasmic mRNAs. It is thought that the protein remains associated with spliced mRNAs as a tag to indicate where introns had been present, thus coupling pre- and post-mRNA splicing events. Previously, it was thought that two genes encode this protein, RBM8A and RBM8B; it is now thought that the RBM8B locus is a pseudogene. Two alternative start codons result in two forms of the protein, and this gene also uses multiple polyadenylation sites.

MAGOHB; MAGOH; UBC; SUZ12; RNF2; PARK2; SRPK2; SRPK1; FBXO25; tat; UPF3B; SMG9; SMG8; PABPC1; UPF2; SMG5; SMG1; RUVBL2; RBM8A; SMG7; EIF4A3; TTI1; RUVBL1; UPF1; NCBP2; TOE1; SF3B2; RPS16; RPL11; HBB; GSPT1; ZFP36L1; UNC119B; SLIRP; LSM2; CIAPIN1; TFCP2L1

FITC: Fluorescein Isothiocyanate

Polyclonal Antibody

IHC, WB

There is BioGPS gene expression data showing that RBM8A is expressed in Jurkat

0.5 mg/ml

Cow: 100%; Dog: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 82%; Rabbit: 82%; Rat: 100%; Zebrafish: 100%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

19kDa

Hsu, Ia.W., (2005) J. Biol. Chem. 280 (41), 34507-34512

Wet Ice

174

RBM8A

RBM8A

Rabbit

RNA-binding protein 8A

NM_005105

LHEAGGEDFAMDEDGDESIHKLKEKAKKRKGRGFGSEEGSRARMREDYDS