RCHY1 Antilichaam - N-terminalgebied: FITC (ARP42973_P050-FITC)

Ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase

ZCHY, ARNIP, CHIMP, PIRH2, RNF199, ZNF363, PRO1996

25898

Q96PM5

NP_001008925

Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit, Sheep

The immunogen is a synthetic peptide directed towards the N terminal region of human RCHY1

RCHY1 has ubiquitin-protein ligase activity. This protein binds with p53 and promotes the ubiquitin-mediated proteosomal degradation of p53. This gene is oncogenic because loss of p53 function contributes directly to malignant tumor development. Transcription of this gene is regulated by p53.The protein encoded by this gene has ubiquitin-protein ligase activity. This protein binds with p53 and promotes the ubiquitin-mediated proteosomal degradation of p53. This gene is oncogenic because loss of p53 function contributes directly to malignant tumor development. Transcription of this gene is regulated by p53. Alternative splicing results in multiple transcript variants encoding different isoforms.

MEOX2; NOTCH2NL; UBASH3B; KRTAP9-2; LIMS2; SEMA4C; WDR74; ADAMTSL4; RCHY1; PGLS; KLHL41; MDM2; TAOK2; TP53; UBC; RNF2; HOXA2; YWHAE; CDK9; DCUN1D5; RILP; TMBIM1; CHD8; USP28; C19orf80; RBM38; NLK; TMEM14C; AIG1; SERTAD1; CHEK2; PRDX4; RAB11A; FADS6; TMEM1

FITC: Fluorescein Isothiocyanate

Polyclonal Antibody

WB

Affinity Purified

RCHY1 is strongly supported by BioGPS gene expression data to be expressed in Jurkat

0.5 mg/ml

Cow: 100%; Dog: 100%; Horse: 100%; Human: 100%; Mouse: 93%; Pig: 93%; Rabbit: 100%; Rat: 100%; Sheep: 100%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

23kDa

Maruyama, S., Mol. Cell. Biochem. 307 (1-2), 73-82 (2008)

Wet Ice

200

RCHY1

RCHY1

Rabbit

RING finger and CHY zinc finger domain-containing protein 1

NM_001008925

KLYTCRLCHDNNEDHQLDRFKVKEVQCINCEKIQHAQQTCEECSTLFGEY