Recombinant Actin-α1 Monoklonale Antilichaam

Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Three transcript variants encoding different isoforms have been found for this gene.

Actinin-α1

P12814

Human; Mouse; Rat

Recombinant Human Actinin-α1 protein

ACTN; Non-muscle alpha-actinin; BDPLT; ACTN1; BDPLT15; Alpha-actinin cytoskeletal isoform; F-actin cross-linking protein; Non-muscle alpha-actinin-1; actinin; actinin 1 smooth muscle; Actinin alpha 1; ACTN 1; alpha 1; Alpha Actinin 1; Alpha actinin cytoskeletal isoform; Alpha-actinin-1; F actin cross linking protein; FLJ40884; FLJ54432; Non muscle alpha actinin 1; Actinin-α1

4D11

Unconjugated

IHC

Signal Transduction; Stem Cells; Developmental Biology

Protein A

0.2 mg/mL

IHC 1:200-1:1000

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Ice bag

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

https://789.bio/eb/bXmA5tZ7

IgG, κ