Recombinant Actin-α2 Monoklonale Antilichaam

Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a muscle-specific, alpha actinin isoform that is expressed in both skeletal and cardiac muscles. Several transcript variants encoding different isoforms have been found for this gene.

Actinin-α2

P35609

Human; Mouse; Rat

Recombinant Human Actinin-α2 protein

CMH; ACTN; ACTN2; CMD1AA; CMH23; Actin binding protein; actinin alpha 2; ACTN 2; Alpha actinin 2; Alpha actinin skeletal muscle; Alpha actinin skeletal muscle isoform 2; Alpha-actinin skeletal muscle isoform 2; Alpha-actinin-2; F actin cross linking protein; F-actin cross-linking protein; Actinin α2

1A6

Unconjugated

WB

Signal Transduction; Cardiovascular

Protein A

0.2 mg/mL

WB 1:500-1:2000

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Ice bag

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

https://789.bio/eb/7lVgrXHQ

104 kDa

104 kDa

IgG, κ