Recombinant ATP-Citrate Lyase Monoklonale Antilichaam

ATP citrate lyase (ACLY) Homo sapiens ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Multiple transcript variants encoding distinct isoforms have been identified for this gene.

ATP-Citrate Lyase

P53396

Human; Mouse; Rat

Recombinant Human ATP-Citrate Lyase protein

OTTHUMP; ACLY; ACL; ATPCL; CLATP; ATP citrate (pro-S) lyase; ATP citrate lyase; ATP citrate synthase; ATP-citrate (pro-S-) -lyase; ATPcitrate synthase; ATP-citrate synthase; Citrate cleavage enzyme; OTTHUMP00000164773; ATP-citrate synthase

2D13

Unconjugated

WB; IHC

Signal Transduction; Cancer; Metabolism

Protein A

0.2 mg/mL

IHC 1:2000-1:10000; WB 1:2000-1:10000

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Ice bag

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

https://789.bio/eb/OPMzijM5

121 kDa

121 kDa

IgG, κ